Asianomics Group's Jim Walker, who predicted the yuan's four-year advance would end a month before the currency peaked in January 2014, is forecasting a US recession.
Raoul Pal, publisher of the Global Macro Investor report and a yuan bear since 2012, says European bank shares will tumble by half.
John Mauldin, of Millennium Wave Advisors, who has argued since 2011 that the Chinese currency should weaken, sees the risk of heightened geopolitical instability in the Middle East as lower crude prices strain the budgets of oil-rich countries.
"There's a storm of troubles coming," said Mr Pal, a former hedge-fund manager at GLG Partners whose clients now include pension plans and sovereign wealth funds.
"The risk of a very bad outcome in 2016 and 2017 remains the highest probability," he said.
Mr Walker predicts gold will surge more than 60 per cent to US$2,000 an ounce this year as investors flock to haven assets. "It's not looking good for the US," he said in Hong Kong.
These predictions are out of step with the consensus. The median forecasters tracked by Bloomberg see US growth of more than two per cent this year, while they project gold will end the year at $1,115 an ounce.
For Mr Pal, there's more scope for turmoil in Europe's banking system after disappointing earnings from Credit Suisse and Deutsche Bank helped send the region's financial shares tumbling this year.
He says stock prices in the industry may fall 50 per cent over the next 18 months as banks' derivative, currency and energy holdings sour. Pal has also advised clients to buy credit-default swaps on European lenders, calling bankruptcies or government bailouts a key "black swan" risk this year.
Mr Mauldin, who reiterated the case for a China devaluation in a June 2015 book on the nation's economy, is now focused on the ramifications of oil's collapse on the Middle East.
The 45 per cent plunge in Brent crude over the past 12 months has dragged down regional equity markets, prompted Saudi Arabia to cut spending and spurred bets that the country will abandon its currency peg to the US dollar.
"I'm very concerned about the House of Saud losing its grip on power under financial stress and budget cuts, and sending the whole region into chaos," Mr Mauldin said.